Which tablet is best for blocked nose? Antihistamines Cetirizine (Zyrtec) Chlorpheniramine (Chlor-Trimeton) Clemastine (Tavist) Desloratadine (Clarinex) Diphenhydramine (Benadryl) Fexofenadine (Allegra) Loratadine (Claritin) Apr 4, 2016