How much doxycycline should I take for a sinus infection?

For sinusitis, clinical practice guidelines recommend 100 mg PO twice daily or 200 mg PO once daily for 5 to 7 days as second line therapy or for patients with a beta-lactam allergy. 100 mg PO every 12 hours on day 1, then 100 mg PO once daily. For severe infections, use 100 mg PO every 12 hours.

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