How long should I take doxycycline for Lyme?

Treatment for 10 to 14 days is recommended (10 d for doxycycline and 14 d for amoxicillin, cefuroxime axetil, or phenoxymethylpenicillin). Longer treatment was previously recommended. Erythema migrans typically shows improvement within a few days after the institution of appropriate antibiotic therapy.Apr 5, 2021

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