How long does it take for doxycycline to work on acne?

Like other acne treatments, doxycycline needs some time to start working. Your acne might start improving within 2 weeks, but it can take up to 12 weeks (or 3 months) to see the full benefit of the treatment. You’ll know doxycycline is working for you when you see less acne forming and your skin starts to look clearer.Sep 30, 2019

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