In patients with confirmed C. difficile infection, the offending antibiotic should be withdrawn. The recommended antibiotic is metronidazole (Flagyl) in a dosage of 250 mg orally four times per day or 500 mg orally three times per day for 10 to 14 days.Mar 1, 2005
The UVA researchers found that the immune response to C. diff causes tissue damage and even death through a type of immune cell called Th17. This solves a longstanding mystery about why disease severity does not correlate with the amount of bacteria in the body but, instead, to the magnitude of the immune response.Apr 23, 2019
It is common for people to get a C-diff infection again—maybe several times—after the first infection. If this happens, your doctor may prescribe another round of the same or different antibiotic, or may try different doses or combinations of these medicines.Dec 19, 2011
The best way to be sure you don't get C. diff again is to work with your healthcare professional to avoid taking unnecessary antibiotics and to wash your hands with soap and water every time you use the bathroom and before you eat anything. If you've had a C. diff infection, tell your healthcare professional.Jul 12, 2021
What should you limit or remove from your diet?
- cruciferous vegetables, such as broccoli, cabbage, cauliflower, and Brussels sprouts.
- raw vegetables of any kind.
- spicy food.
- fried or greasy food.
- caffeinated beverages.
- food with a high fat content, such as mayonnaise.
What are the risk factors for recurrent C. difficile? Risk factors for recurrence of C. difficile include older age (older than 65 years), female sex, Caucasian ethnicity, ongoing antibiotic use, concurrent proton pump inhibitor use, and more severe initial disease.Nov 18, 2019
People with Clostridium difficile infections typically recover within two weeks of starting antibiotic treatment. However, many people become reinfected and need additional therapy. Most recurrences happen one to three weeks after stopping antibiotic therapy, although some occur as long as two or three months later.
If Flagyl is ineffective, then Vancocin (vancomycin) is prescribed. In rare cases, C. diff may not respond well to antibiotics, with infections persisting for months and even years. New studies have shed light on a treatment that was once considered a last resort by many doctors.